N-[(1,1-Dimethylethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-L-ornithinamide

Name	Boc-Val-Cit-PABA
Synonyms	Boc-Val-Cit-PABA Boc-Val-Cit-PAB-OH Boc-Gly-Gly-Phe-Gly Pentanoicacid,2,6-dioxo-,methylester (S)-2-[(S)-2-(Boc-amino)-3-methylbutanamido]-N-[4-(hydroxymethyl)phenyl]-5-ureidopentanamide N-[(1,1-Dimethylethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-L-ornithinamide L-Ornithinamide, N-[(1,1-dimethylethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]- tert-butyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxo-5-ureidopentan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate
CAS	870487-09-5

Molecular Formula	C23H37N5O6
Molar Mass	479.57
Density	1.209±0.06 g/cm3(Predicted)
Boling Point	771.3±60.0 °C(Predicted)
pKa	11.25±0.46(Predicted)
Storage Condition	2-8°C
Physical and Chemical Properties	Bioactive Boc-Val-Cit-PAB is a degradable (cleavable) ADC linker that can be used to synthesize antibody-coupled drugs (ADC).
Use	The Boc-Val-Cit-PAB of use is a cleavable ADC linker for the synthesis of antibody-drug conjugates (ADCs).
In vitro study	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
In vivo study	The ADC is composed of an antibody, and the ADC cytotoxin is bound to the antibody via the ADC linker.

Last Update：2024-01-02 23:10:35

In vivo studies

ADC is composed of antibodies, which bind ADC cytotoxins to antibodies through ADC connectors.

Target

Cleavable

in vitro studies

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

Last Update：2024-04-09 01:59:50

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

use	Boc-Val-Cit-PAB are cleavable ADC connectors for the synthesis of antibody-drug conjugates (ADC).
in vivo study	ADC consists of antibodies, which bind ADC cytotoxins to antibodies through ADC connectors.
biological activity	Boc-Val-Cit-PAB is a degradable (cleavable) ADC linker that can be used to synthesize antibody-coupled drugs (ADC).
target	Cleavable
in vitro study

Last Update：2024-04-09 01:59:58

Product Name: Boc-Val-Cit-PABA；Boc-Val-Cit-PAB Visit Supplier Webpage Request for quotation
CAS: 870487-09-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409

Wechat: 18301782025

Product Name: Boc-Val-Cit-PABA；Boc-Val-Cit-PAB Visit Supplier Webpage Request for quotation
CAS: 870487-09-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409

Wechat: 18301782025

View History

N-[(1,1-Dimethylethoxy)carbonyl]-L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-L-ornithinamide Request for Quotation